Splines And Compartment Models: An Introduction

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Splines And Compartment Models: An Introduction

Name: Splines And Compartment Models: An Introduction
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Rating: 4.4 (26 reviews)
Author: Karl-ernst Erich Biebler and Michael Wodny
ISBN: 9789814522229

by Karl-ernst Erich Biebler and Michael Wodny

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Creators

Author Karl-ernst Erich Biebler and Michael Wodny

Publisher World Scientific Publishing Co Pte Ltd

Synopsis This book presents methods of mathematical modeling from two points of view. Splines provide a general approach while compartment models serve as examples for context related to modeling. The preconditions and characteristics of the developed mathematical models as well as the conditions surrounding data collection and model fit are taken into account. The substantial statements of this book are mathematically proven. The results are ready for application with examples and related program codes given. In this book, splines are algebraically developed such that the reader or user can easily understand and vary the numerical construction of the different kinds of spline functions. The classical compartment models of the pharmacokinetics are systematically analyzed and connected with lifetime distributions. As such, parameter estimation and model fit can be treated statistically with a varied minimum chi-square method. This method is applicable for single kinetics and also allows the calculation of average kinetics.

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Binding: Hardcover

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Specifications

Language: English
Publisher: World Scientific Publishing Co Pte Ltd
Pages: 348 pages
Binding: Hardcover

ISBN: 9789814522229
Category: Mathematics & logic
Related Category: Natural Sciences